Catalysis Database

Zeolite catalysed intramolecular cyclization of 5-amino-1-pentanol to piperidine bases

B N , Reddy and S J, Kulkarni and M. , Subrahmanyam (1994) Zeolite catalysed intramolecular cyclization of 5-amino-1-pentanol to piperidine bases. Applied Catalysis A: General, 119 (1). pp. 22-32.

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Official URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TF5-43S78XJ-S&_user=518931&_coverDate=11%2F10%2F1994&_alid=590951277&_rdoc=80&_fmt=full&_orig=search&_cdi=5217&_sort=d&_docanchor=&view=c&_ct=151&_acct=C000025838&_version=1&_urlVersion=0&_userid=

Abstract

5-amino-1-pentanol (5-AP) undergoes facile intramolecular cyclocondensation to piperidine and to methyl or ethyl piperidines in the presence of methanol or ethanol over zeolite catalysts like ZSM-5 (Si/Al = 30, 129, 280), HM and HY. 2-Aminopyran (2-AP) is also observed as a major product in the conversion of 5-AP to piperidine on the ZSM-5 (280) and HY. Piperidine and N-methylpiperidine are predominantly formed over HY zeolite with near total conversion (98%) of 5-AP in the 5-AP alkylation with methanol. 2-Methyl piperidine is also formed as a side product in this reaction over all the zeolites studied. Methanol conversion does not show any trend. The HY catalyst is also studied for its ethylation activity of 5-AP with ethanol to synthesize ethyl piperidine bases. The effects of temperature and W/F factor on the conversion of 5-AP and ethanol and also on the yields of ethylpiperidines is presented. The possible schemes for the cyclocondensation of 5-AP and alkylation with methanol and ethanol are discussed. No dehydrogenated products (pyridine, picolines and ethylpyridines) are observed in these condensation reactions.

Item Type:Article
Uncontrolled Keywords:Alkylation; 5-Amino-1-pentanol; Condensation; Cyclocondensation; Ethanol; Methanol; Methyl(ethyl) piperidines; Piperidine; W/F factor; Zeolites
Subjects:Science > Chemistry
ID Code:936
Deposited By:Prof Balasubramanian Viswanathan
Deposited On:20 Jun 2007 11:21
Last Modified:20 Jun 2007 11:21

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