Asymmetric addition of trimethylsilyl cyanide to aldehydes promoted by chiral polymeric vanadium(V) salen complex as an efficient and recyclable catalyst

N H, Khan and Santosh , Agrawal and R I, Kureshy and S.H.R., Abdi and Vishal J, Mayani and R V , Jasra (2006) Asymmetric addition of trimethylsilyl cyanide to aldehydes promoted by chiral polymeric vanadium(V) salen complex as an efficient and recyclable catalyst. Tetrahedron: Asymmetry , 17 (18). pp. 2659-2666.

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Official URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6THT-4M7K9PS-7&_user=518931&_coverDate=10%2F16%2F2006&_alid=589647082&_rdoc=4&_fmt=full&_orig=search&_cdi=5291&_sort=d&_docanchor=&view=c&_ct=28&_acct=C000025838&_version=1&_urlVersion=0&_userid=51

Abstract

The asymmetric addition of trimethylsilyl cyanide to various aldehydes catalyzed by efficient new vanadyl polymeric salen complexes having 12 repeating salen units was investigated at room temperature. An excellent yield of the trimethylsilylether of cyanohydrins (up to 98%) with high chiral induction (96%) in case of 2-methylbenzaldehyde was achieved in 18 h. The catalyst recovered four times with retention of its performance.

Item Type:	Article
Subjects:	Science > Chemistry
ID Code:	924
Deposited By:	Prof Balasubramanian Viswanathan
Deposited On:	16 Jun 2007 15:12
Last Modified:	16 Jun 2007 15:12

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